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1

HP 663: A novel compound for the treatment of glaucoma

Harold B. Hartman, Joachim E. Roehr, Bernard L. Kotyuk, Raymond W. Kosley Jr., Robert J. Cherill, Wayne W. Petko, Paul G. Conway

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 785 KB

english, 1988

2

Vascular and cardiac effects of HP 406 and nifedipine in vitro and in conscious spontaneously hypertensive rats and renal hypertensive dogs

John W. Hubbard, Joan F. Kapples, Scott T. Nordstrom, Laura C. Matson, Sandy J. Wilson, Rudyard J. Ress, Raymond W. Kosley Jr., Robert J. Cherill, Francis P. Huger, Stuart Fielding

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 804 KB

english, 1988

3

Stereoselective synthesis of functionalized olefins: The orthoester claisen rearrangement of alkynyl allylic alcohols

Kathlyn A. Parker, Raymond W. Kosley Jr.

Journal:

Tetrahedron Letters

Year:

1975

Language:

english

File:

PDF, 181 KB

english, 1975

4

A new dienamine syhthesis; The amide acetal claisen rearrangement of alkynyl allylic alcohols

Kathlyn A. Parker, Raymond W. Kosley Jr.

Journal:

Tetrahedron Letters

Year:

1975

Language:

english

File:

PDF, 103 KB

english, 1975

5

The amide acetal condensation of propargyl alcohols: synthesis of γ-keto esters and silyl allenes under mild conditions

Kathlyn A. Parker, Raymond W. Kosley Jr.

Journal:

Tetrahedron Letters

Year:

1976

Language:

english

File:

PDF, 200 KB

english, 1976

6

Use of the diels-alder reaction as a criterion of aromaticity in 4-heteracyclohexa-2,5-dienones

Jerry A. Hirsch, Raymond W. Kosley Jr., Richard P. Morin, George Schwartzkopf, Ronald D. Brown

Journal:

Journal of Heterocyclic Chemistry

Year:

1975

File:

PDF, 109 KB

1975

7

Synthesis of 1,2′,3,3′,5′,6′-hexahydro-3-phenylspiro[isobenzofuran-1,4′-thiopyrans] and 1,2′,3,3′,5′,6′-hexahydro-3-phenylspiro-[isobenzofuran-1,4′-pyrans]

Victor J. Bauer, Helen H. Ong, Raymond W. Kosley Jr.

Journal:

Journal of Heterocyclic Chemistry

Year:

1982

File:

PDF, 313 KB

1982

8

Reactions of propargyl alcohols with amide acetals

Parker, Kathlyn A., Petraitis, Joseph J., Kosley, Raymond W., Buchwald, Stephen L.

Journal:

Journal of Organic Chemistry

Year:

1982

Language:

english

File:

PDF, 1.14 MB

english, 1982

9

N -Tosyl- l -phenylalanine Chloromethyl Ketone, a Serine Protease Inhibitor, Identifies Glutamate 398 at the Coenzyme-Binding Site of Human Aldehyde Dehydrogenase. Evidence for a Second “Naked Anion” at the Active Site †

Dryjanski, Marek, Kosley, Lynda L., Pietruszko, Regina

Journal:

Year:

1998

Language:

english

File:

PDF, 132 KB

english, 1998

10

Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 1

Bauer, Victor J., Duffy, Brian J., Hoffman, David, Klioze, Solomon S., Kosley, Raymond W., McFadden, Arthur R., Martin, Lawrence L., Ong, Helen H., Geyer, Harry M.

Journal:

Journal of Medicinal Chemistry

Year:

1976

Language:

english

File:

PDF, 1.15 MB

english, 1976

11

(Aminoalkyl)carbamates of forskolin: intermediates for the synthesis of functionalized derivatives of forskolin with different specificities for adenylyl cyclase and the glucose transporter

Robbins, Joan D., Laurenza, Antonio, Kosley, Raymond W., O'Malley, Gerard J., Spahl, Bettina, Seamon, Kenneth B.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 1.77 MB

english, 1991

12

Human aldehyde dehydrogenase: coenzyme binding studies

Ambroziak, Wojciech, Kosley, Lynda L., Pietruszko, Regina

Journal:

Year:

1989

Language:

english

File:

PDF, 884 KB

english, 1989

13

Regioselective acylations of 7-desacetylforskolin

Kosley, Raymond W., Cherill, Robert J.

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 551 KB

english, 1989

14

The reaction of tertiary ethynyl alcohols with formamide acetals: formation of dienamines and enamine orthoformates

Parker, Kathlyn A., Kosley, Raymond W., Buchwald, Stephen L., Petraitis, Joseph J.

Journal:

Journal of the American Chemical Society

Year:

1976

Language:

english

File:

PDF, 232 KB

english, 1976

15

Regiocontrolled reactions of 7-desacetylforskolin. 2. Synthesis of 6- and 7-carbamate derivatives

O'Malley, Gerard J., Spahl, Bettina, Cherill, Robert J., Kosley, Raymond W.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 513 KB

english, 1990

16

Adenylate Cyclase Stimulation and Intraocular Pressure Reduction by Forskolin Analogs

CAPRIOLI, JOSEPH, SEARS, MARVIN, MEAD, ALDEN, KOSLEY, RAYMOND W., CHERILL, ROBERT J., HUGER, FRANCIS P., ALLEN, RICHARD C., TRESSLER, CHARLES

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

1989

Language:

english

File:

PDF, 516 KB

english, 1989

17

ChemInform Abstract: Regiocontrolled Reactions of 7-Desacetylforskolin. Part 2. Synthesis of 6- and 7-Carbamate Derivatives.

O'MALLEY, G. J., SPAHL, B., CHERILL, R. J., KOSLEY, R. W. JUN.

Journal:

Year:

1990

File:

PDF, 73 KB

1990

18

ChemInform Abstract: THE AMIDE ACETAL CONDENSATION OF PROPARGYL ALCOHOLS. SYNTHESIS OF Γ-KETO ESTERS AND SILYL ALLENES UNDER MILD CONDITIONS

PARKER, K. A., KOSLEY, R. W. JUN.

Journal:

Chemischer Informationsdienst

Year:

1976

File:

PDF, 127 KB

1976

19

ChemInform Abstract: SYNTHESIS OF 1,2′,3,3′,5′,6′-HEXAHYDRO-3-PHENYLSPIRO(ISOBENZOFURAN-1,4′-THIOPYRANS) AND 1,2′,3,3′,5′,6′-HEXAHYDRO-3-PHENYLSPIRO(ISOBENZOFURAN-1,4′-PYRANS)

BAUER, V. J., ONG, H. H., KOSLEY, W. JUN.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 229 KB

1983

20

ChemInform Abstract: USE OF THE DIELS-ALDER REACTION AS A CRITERION OF AROMATICITY IN 4-HETERACYCLOHEXA-2,5-DIENONES

HIRSCH, J. A., KOSLEY, R. W. JUN., MORIN, R. P., SCHWARTZKOPF, G., BROWN, R. D.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 126 KB

1975

21

ChemInform Abstract: THE REACTION OF TERTIARY ETHYNYL ALCOHOLS WITH FORMAMIDE ACETALS- FORMATION OF DIENAMINES AND ENAMINE ORTHOFORMATES

PARKER, K. A., KOSLEY, R. W. JUN., BUCHWALD, S. L., PETRAITIS, J. J.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 221 KB

1977

22

ChemInform Abstract: A NEW DIENAMINE SYNTHESIS, THE AMIDE ACETAL CLAISEN REARRANGEMENT OF ALKYNYL ALLYLIC ALCOHOLS

PARKER, K. A., KOSLEY, R. W. JUN.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 118 KB

1975

23

ChemInform Abstract: SYNTHESIS OF SPIRO(ISOBENZOFURAN-1(3H),4′-PIPERIDINES) AS POTENTIAL CENTRAL NERVOUS SYSTEM AGENTS. 1

BAUER, V. J., DUFFY, B. J., HOFFMAN, D., KLIOZE, S. S., KOSLEY, R. W. JUN., MCFADDEN, A. R., MARTIN, L. K., ONG, H. H., GEYER, H. M.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 242 KB

1977

24

Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators

Vaz, Roy J., Li, Yi, Chellaraj, Vinolia, Reiling, Stephan, Kuntzweiler, Theresa, Yang, Donglai, Shen, Hong, Batchelor, Joseph D., Zhang, Ying, Chen, Xin, McLean, Larry, Kosley, Raymond

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 731 KB

english, 2018

25

ChemInform Abstract: REACTIONS OF PROPARGYL ALCOHOLS WITH AMIDE ACETALS

PARKER, K. A., PETRAITIS, J. J., KOSLEY, R. W. JUN., BUCHWALD, S. L.

Journal:

Chemischer Informationsdienst

Year:

1982

File:

PDF, 260 KB

1982

26

ChemInform Abstract: STEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED OLEFINS, THE ORTHOESTER CLAISEN REARRANGEMENT OF ALKYNYL ALLYLIC ALCOHOLS

PARKER, K. A., KOSLEY, R. W. JUN.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 104 KB

1975

27

ChemInform Abstract: SYNTHESIS OF SPIRO(ISOBENZOFURAN-1(3H),4′-PIPERIDINES) AS POTENTIAL CENTRAL NERVOUS SYSTEM AGENTS. 4. CENTRAL NERVOUS SYSTEM DEPRESSANTS

ALLEN, R. C., BAUER, V. J., KOSLEY, R. W., MCFADDEN, A. R., SHUTSKE, G. M., CORNFELDT, M. L., FIELDING, S., GEYER, H. M., WILKER, J. C.

Journal:

Chemischer Informationsdienst

Year:

1979

File:

PDF, 224 KB

1979